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Study of 100,000 Australians seeks causes of mental health disorders and early onset cancer

By · Via The Guardian · Published by Everything Blog

In short

The Sax Institute's new 18 and Up study aims to recruit 100,000 individuals between the ages of 18 and 45 to investigate rising rates of mental illness and early-onset cancers. Recruitment launches in November, supported by a $4.5 million grant from the National Health and Medical Research Council. Researchers will enroll the children and grandchildren of participants from the institute's previous 45 and Up study, which tracked more than 267,000 older Australians. Participant surveys will be combined with cancer registries and Medicare records to identify how lived experiences and family backgrounds shape long-term health.

Key points

  • The 18 and Up project will follow participants across their lifespans to understand root…: The 18 and Up project will follow participants across their lifespans to understand root drivers of emerging conditions and future pandemics.
  • Enrolling the offspring of 45 and Up participants allows researchers to evaluate how heal…: Enrolling the offspring of 45 and Up participants allows researchers to evaluate how health traits and social conditions pass across generations.
  • Findings from this large-scale tracking effort are intended to guide preventative interve…: Findings from this large-scale tracking effort are intended to guide preventative interventions and broad reforms throughout health and care systems.

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Researchers hope to better understand the drivers of major health challenges facing younger people, such as mental illness and rising cancer rates, through the recruitment of 100,000 people for Australia’s largest intergenerational study of wellbeing and ageing.

The independent and not-for-profit research institute the Sax Institute, on Thursday launched the 18 and Up study, which will follow the health of those aged 18 to 45 throughout their lives.

Two decades ago, the institute started 45 and Up, now the largest population-based cohort study in the southern hemisphere, with more than 267,000 participants ranging in age from 45 to older than 100.

Since then, participants have been repeatedly surveyed and their responses linked to other datasets, leading to significant discoveries about smoking, dementia prevention, and differences in cardiovascular outcomes between men and women.

18 and Up’s scientific director, Adjunct Prof Justine Gatt, said there was a lack of long-term data for younger generations, with existing studies often only giving researchers information from a snapshot in time.

“Almost two in five young Australians aged 16 to 24 experienced a mental disorder in…

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