Michael Charlton, a physician and former senior vice president at Madrigal Pharmaceuticals, filed the federal lawsuit on Oct. 9 in the Northern District of Illinois. He alleges that company leadership suppressed safety concerns regarding its approved MASH liver disease drug and unlawfully retaliated against him under whistleblower statutes. Charlton is currently asking the court for either complete job reinstatement or monetary damages.
Key points
A former clinical development chief is pursuing reinstatement or monetary damages over an…: A former clinical development chief is pursuing reinstatement or monetary damages over an alleged constructive discharge.
The lawsuit asserts that Madrigal Pharmaceuticals actively concealed safety issues relate…: The lawsuit asserts that Madrigal Pharmaceuticals actively concealed safety issues related to its approved liver disease medication.
Whistleblower protections form the core legal foundation of the federal complaint lodged…: Whistleblower protections form the core legal foundation of the federal complaint lodged against the pharmaceutical firm.
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A top former executive at Madrigal Pharmaceuticals has filed a lawsuit in federal court alleging he was forced to resign after raising internal concerns about the safety of the company’s approved medication for patients with the liver disease known as MASH.
Michael Charlton, a physician, was Madrigal’s senior vice president, head of clinical development, from October 2024 until January 2026. His lawsuit, filed on Oct. 9 in the Northern District of Illinois, accuses Madrigal of retaliation under federal whistleblower-protection statutes and seeks reinstatement or monetary damages.
“[Charlton’s] mandate was to safeguard the safety, scientific integrity and accuracy of the clinical trials and disclosures supporting Madrigal’s flagship drug. He did exactly that. Madrigal punished him for it,” the lawsuit alleges.
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