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• STAT+: Patient dies in Bristol Myers Squibb autoimmune CAR-T trial

  A patient at Bristol Myers Squibb's early autoimmune CAR-T trial died following treatment, experiencing motor symptoms that did not improve despite standard treatments. The patient was given an immunosuppressant but developed septic pneumonia, leading to their death. This incident underscores safety concerns in CAR-T autoimmune trials and highlights the need for continued monitoring and improvement in treatment protocols.

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• STAT+: Most cancer drugs approved by European regulators lack a high clinical benefit, analysis finds

  A new analysis of cancer drugs approved by European regulators finds that most treatments lack high clinical benefits, with only 31% of 97 approved indications meeting the criteria. This highlights a "fundamental shift in the innovation ecosystem" and suggests that five drugmakers, primarily based in China and Japan, account for more than half of the top clinical benefit indications.

  1 min read
• Celebrated Irish musician Dónal Lunny dies aged 79

  Celebrated Irish musician Dónal Lunny, a founding member of three renowned bands and a pioneer of traditional Irish music, has passed away at the age of 79. Lunny, born in 1947, was a key figure in the revival and growth of Irish traditional music and was widely credited for leaving a lasting impact on the music scene in Ireland. Lunny's career was built on creativity, friendship, and collaboration, and he was presented with a lifetime achievement award at the BBC Radio 2 Folk Awards in 2018.

  3 min read