Nature, Published online: 25 October 2026; doi:10.1038/s41586-026-11328-3 ctDNA clearance and outcomes for resectable lung cancer from NeoCOAST-2
ctDNA clearance and outcomes for resectable lung cancer from NeoCOAST-2
In short
### Briefing In a recent study titled "ctDNA clearance and outcomes for resectable lung cancer from NeoCOAST-2," researchers investigated the relationship between the clearance of circulating tumor DNA (ctDNA) and patient outcomes in resectable lung cancer. The study, published online on October 25, 2026, in the journal *Nature*, analyzed data from the NeoCOAST-2 trial, which aimed to evaluate the efficacy of targeted therapies in patients with resectable lung cancer. The key findings of the study indicate that p…
Key points
- ### Briefing In a recent study titled "ctDNA clearance and outcomes for resectable lung…: ### Briefing In a recent study titled "ctDNA clearance and outcomes for resectable lung cancer from NeoCOAST-2," researchers investigated the relationship between the clearance of circulating tumor DNA (ctDNA) and patient outcomes in resec
- The study, published online on October 25, 2026, in the journal *Nature*, analyzed data f…: The study, published online on October 25, 2026, in the journal *Nature*, analyzed data from the NeoCOAST-2 trial, which aimed to evaluate the efficacy of targeted therapies in patients with resectable lung cancer.
- The key findings of the study indicate that patients who achieved ctDNA clearance had sig…: The key findings of the study indicate that patients who achieved ctDNA clearance had significantly better overall survival rates compared to those who did not clear ctDNA.