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ctDNA clearance and outcomes for resectable lung cancer from NeoCOAST-2

By · Via Nature · Published by Everything Blog

In short

### Briefing In a recent study titled "ctDNA clearance and outcomes for resectable lung cancer from NeoCOAST-2," researchers investigated the relationship between the clearance of circulating tumor DNA (ctDNA) and patient outcomes in resectable lung cancer. The study, published online on October 25, 2026, in the journal *Nature*, analyzed data from the NeoCOAST-2 trial, which aimed to evaluate the efficacy of targeted therapies in patients with resectable lung cancer. The key findings of the study indicate that p…

Key points

  • ### Briefing In a recent study titled "ctDNA clearance and outcomes for resectable lung…: ### Briefing In a recent study titled "ctDNA clearance and outcomes for resectable lung cancer from NeoCOAST-2," researchers investigated the relationship between the clearance of circulating tumor DNA (ctDNA) and patient outcomes in resec
  • The study, published online on October 25, 2026, in the journal *Nature*, analyzed data f…: The study, published online on October 25, 2026, in the journal *Nature*, analyzed data from the NeoCOAST-2 trial, which aimed to evaluate the efficacy of targeted therapies in patients with resectable lung cancer.
  • The key findings of the study indicate that patients who achieved ctDNA clearance had sig…: The key findings of the study indicate that patients who achieved ctDNA clearance had significantly better overall survival rates compared to those who did not clear ctDNA.

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Nature, Published online: 25 October 2026; doi:10.1038/s41586-026-11328-3 ctDNA clearance and outcomes for resectable lung cancer from NeoCOAST-2

Original source: www.nature.com

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